Principal Investigator (PI)

About the job

Pay: $18–$36 per hour (₹1,500–₹3,000 per hour)

Engagement: Part-time | Contract (3–4 hours/week)

Location: Delhi

About VI Signal Inc.

VI Signal Inc. is developing FaceEcho, an AI-powered facial scan and questionnaire-based application designed to identify visual patterns associated with wellness and health-related indicators. The platform uses structured front-face, multi-angle, and guided video scans combined with symptom questionnaires to generate pattern-based insights.

The system is non-diagnostic and intended to support research, early signal detection, and follow-up recommendations such as consultation or laboratory evaluation. The current study aims to evaluate the accuracy, consistency, and safety of these pattern-based observations while ensuring ethical deployment and appropriate clinical oversight.

The study will be conducted as a clinical accuracy and research validation effort focusing on scientific rigor, participant safety, and responsible use of AI-based pattern detection.

This study will be conducted in India, with a preference for Maharashtra, while supporting a predominantly remote participation model with some guided participation where applicable.

Role Summary

We are seeking a Principal Investigator (PI) to provide scientific and ethical oversight for a clinical accuracy study evaluating an AI-based facial scan and questionnaire system.

The study evaluates pattern-based detection signals across multiple wellness and medical-related indicators. The system is non-diagnostic and intended for research and validation purposes.

The PI will be responsible for ensuring ethical compliance, participant safety, scientific validity, and appropriate study governance throughout the study lifecycle, including oversight of study processes, participant safety frameworks, and data interpretation standards.

Key Responsibilities

1. Study Oversight

• Review and approve study protocol
• Validate study objectives and endpoints
• Ensure alignment with non-diagnostic positioning
• Provide guidance on study design considerations

2. Ethics Oversight

Review and approve:

1. User Consent Form
2. Participant Information Sheet
3. Risk Disclosure Statement

Ensure voluntary participation framework

Confirm appropriate participant communication

Oversee participant safety considerations across study settings

3. Clinical Reasonability Review

• Validate inclusion of study conditions
• Confirm plausibility of visual signal detection
• 
  Ensure messaging avoids diagnostic interpretation
• Advise on follow-up recommendation positioning

4. Reviewer Panel Oversight

• Approve reviewer structure (two reviewers and tie-breaker)
• Provide guidance on disagreement resolution
• Oversee consistency of clinical review approach
• Conduct sample-based review of outputs

5. Study Monitoring

• Participate in scheduled weekly checkpoints
• Review sample outputs for safety and consistency
• Ensure ethical compliance throughout the study
• Provide guidance on required adjustments across remote and guided participation formats

6. Documentation & Scientific Contribution

• Protocol approval
• Ethics oversight confirmation
• Study completion acknowledgment (if applicable)
• Contribution to study interpretation, reporting, and scientific outputs (including publication)

Scope of Involvement

The PI will provide oversight and guidance across:

• study ethics
• clinical plausibility
• participant safety
• reviewer alignment
• messaging and communication
• study governance
• interpretation of study findings

Expected Time Commitment

• Approximately 3–4 hours per week during the active study period, including:
• weekly oversight meetings
• sample-based review

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• ethics and safety monitoring
• guidance to reviewer panel
• Additional time may be required for initial protocol review and final study oversight.

Required Qualifications

• MBBS / MD / equivalent medical degree
• Licensed physician (India)
• Experience in clinical practice or research
• Understanding of clinical evaluation studies
• Recent ethics training (e.g., ICMR/National Ethics Guidelines or equivalent)

Preferred Qualifications

• Experience in digital health or AI-based tools
• Prior research oversight experience
• Ethics committee exposure
• Telehealth familiarity
• General Physician / Internal Medicine preferred

Reporting Structure

1) PI Collaborates With:

• Product team
• Research team
• Reviewer doctors

2) PI Oversees:

• Study ethics
• Scientific integrity

3) Deliverables

• Protocol approval
• Ethics review confirmation
• Reviewer structure approval
• Weekly oversight feedback
• Final oversight note
• Contribution to study reporting and publication